The settings I used.
difficulty 50%
Full bad
Full Order
80% hidden
50% phys/Myst
90% Stealth
100% Money
This will give you missions with two rewards...
One is generally an item you have to find and the item you receive for finding it... that will give you two chances a mission to get the item.
I set hidden/stealth just becuase I am a fixer, and enjoy the extra xp for unlocking things.
I was able to clear a couple mill this way, and it certainly has been a nice start for a total newbie to this game!