1 or 2 true "tanks".
1 - 3 competent docs.
The rest could just be 40 people with weapons...and they don't even have to be at the keyboard.
Try running a 131 wrangle on a dozen people for 2 hours, while keepings drains up on a grey mob that all the mindless idiots automatically shoot unless you hold thier hands and explain it to them 1 by 1. Oh and try to land an 85% nano with over 1200 nanoskills that still only lands 1 out of 30 tries. Did I mention all of those only last 3 minutes?
Sure it "helps" but god d*mn it sucks. Rather log on extra characters, drag them out to the spot and press Q while I go out for pizza. I could probably get 4 damage dealers out there, though FC would get mad at me if I did more than 2
Any nano that isn't a long term buff is basically worthless. NTs, cast humid on everyone then log any alt with better attack rating...crats don't log because need 1 of you to run HM and another to run the crit speech since the mas never buff everyone and it saves NCU. Oh and your pets can help, they might hit 1 in 20 times. Same goes for MPs, stick healpets on the tanks and stick demon on the mob...check back every 15 minutes in case pets drop for some reason. Be sure to refresh mochams on people, but don't bother giving NTs one since their nukes won't land regardless. I'm sure they can fit it in between commercials or doing laundry. Engys do the same, run an aura for grins too.